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Red wine can help prevent stroke
damage: study
Washington -
Red wine might work to protect the brain from damage after a
stroke and drinking a couple of glasses a day might provide that
protection ahead of time, U.S. researchers reported on Sunday.
In an effort to better understand how
red wine works, the scientists from Johns Hopkins University fed mice
a moderate dose of a compound found in red grape skins and seeds
before inducing stroke-like damage.
They discovered that the animals
suffered less brain damage than similarly damaged mice who were not
treated with the compound, which is called resveratrol.
"When we pre-treat the animals with
the compound orally, then we observe that we have a significant
decrease in the area of stroke damage by about 40 percent," said
Sylvain Dore, the lead researcher for the study.
Dore
and his research team presented their results from the study, which
was funded in part by the U.S. government, at a Society for
Neuroscience conference in Atlanta.
"What is unique about this study is
we have somewhat identified what can be the specific mechanism," in
the wine that is good for health, Dore said. "Here we are building
cell resistance against free radical damage."
The study showed that resveratrol
increases levels of an enzyme in the brain -- heme oxygenase -- that
was already known to shield nerve cells from damage.
Dore
said the beneficial effects associated with drinking a moderate amount
of red wine could be explained by the fact the wine turns on the heme
oxygenase anti-oxidant system.
"Red wine has been suggested for the
heart. Here what we show is its special effect in stroke and
pre-treatment," Dore said. "It suggests that prophylactic use of wine
could work."
The fermentation process in
wine-making boosts the concentration of resveratrol, Dore said.
But said more studies are needed to
translate the findings from mice into humans.
The amount of wine that must be
consumed in order to reap the benefits of the compound will vary
depending on a person's weight and the concentration of resveratrol in
the wine. But Dore said it will likely work out to about two glasses a
day. -- Reuters Limited
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